陳紅麗,女,1978年1月出生。博士,教授,碩士研究生導(dǎo)師。獲河南省教育廳學(xué)術(shù)技術(shù)帶頭人,河南省高等學(xué)校青年骨干教師等榮譽稱號。獲2021年河南省高等教育教學(xué)成果獎二等獎1項。主持完成校級教學(xué)改革項目2項。主講《生物工程下游技術(shù)》,《醫(yī)學(xué)細胞生物學(xué)》,《藥劑學(xué)》等本科生課程及《生物醫(yī)用材料制備與表征》等研究生課程
聯(lián)系方式
電話:0373-3029887(office)
E-mail:chenhl@xxmu.edu.cn
學(xué)習(xí)、工作經(jīng)歷
受教育經(jīng)歷
2006/08-2009/07,中國醫(yī)學(xué)科學(xué)院生物醫(yī)學(xué)工程研究所,博士
2003/08-2006/06,中國醫(yī)學(xué)科學(xué)院生物醫(yī)學(xué)工程研究所,碩士
1996/09-2001/06,華中科技大學(xué)同濟醫(yī)學(xué)院,學(xué)士
研究工作經(jīng)歷
2009/07-至今新鄉(xiāng)醫(yī)學(xué)院,生命科學(xué)技術(shù)學(xué)院,副教授,教授
2017/09-2018/09美國弗吉尼亞聯(lián)邦大學(xué),訪問學(xué)者
2001/08-2003/08中國醫(yī)學(xué)科學(xué)院藥物研究所,實研
研究方向
生物醫(yī)用材料,組織工程,納米藥物載體
招生方向
生物學(xué):納米醫(yī)學(xué)、生物醫(yī)學(xué)材料與組織工程
生物與醫(yī)藥:納米醫(yī)學(xué)、生物制藥工程
教學(xué)成果
(1)獲2021年河南省高等教育教學(xué)成果獎二等獎1項(第一完成人)
(2)獲2023年河南省“互聯(lián)網(wǎng)+”大學(xué)生創(chuàng)新創(chuàng)業(yè)大賽二等獎(研究生創(chuàng)意組),第一指導(dǎo)教師
主要科研工作
1.具體研究領(lǐng)域
(1)藥物緩控釋體系抗腫瘤,跨屏障機制研究
(2)組織工程支架材料及創(chuàng)傷修復(fù)應(yīng)用研究
2.課題資助
(1)河南省科技攻關(guān)項目:水凝膠復(fù)合內(nèi)外同源載藥外泌體樣納米囊泡修復(fù)放/化療后口腔黏膜炎作用研究(202401-202512,編號,主持)
(2)河南省高等學(xué)校重點科研項目資助計劃:血小板膜仿生納米遞藥系統(tǒng)的構(gòu)建及其跨胎盤屏障機制研究(202201-202312,編號22A310003,主持結(jié)題)
(3)國家自然科學(xué)基金:基于逆轉(zhuǎn)肝癌多藥耐藥的siRNA/化療藥物靶向納米共載體(201501-2017012,編號81401519,主持結(jié)題)
(4)國家自然科學(xué)基金:用于乳腺癌聯(lián)合化療的雙層納米藥物輸送體系的研究(201401-201612,編號U1304819,主持結(jié)題)
3.取得成果
(1)Synthesis, Characterization and In Vivo Efficacy of Biotin- Conjugated Pullulan Acetate Nanoparticles as a Novel Anticancer Drug Carrier,Journal of Biomedical Nanotechnology, 2021年度河南省教育廳科技成果獎(科技論文類)一等獎,第一完成人
4.近期代表性論文
[1] Peng Wang, Mengyuan Wang, Xiangjuan Wei, Liqin Xie, Linqiang Tian, Zhijun Yang, Zhimin Zhou*,Hongli Chen*, International Journal of Biological Macromolecules, 2024, 272:132876
[2] Chunwang Hu, Hongliang Wei*,Hongli Chen*, Bing Zhang, Wenjing Zhang, Gang Wang, Tao Guo, Facile fabrication of temperature/pH dual sensitive hydrogels based on cellulose and polysuccinimide through aqueous amino-succinimide reaction, International Journal of Biological Macromolecules, 2024, 267 :131543
[3] Yongwei Hao, Xue Li, Yuefei Liu, Dalin Liu, Xuehan Zhao, Shenglu Ji ,Hongli Chen *, Yaojia Li *,Manganese doped nanosystem for degrading neutrophil extracellular traps and improving chemotherapy efficiency to synergistically,Chemical Engineering Journal,2023,466:142957
[4]胡丹慧,潘玉雪,王鵬,焦振娜,萬國運,王海蛟,隨俊慧,唐紅波,陳紅麗*,血小板膜仿生納米載體的制備和表征及其體外跨胎盤細胞屏障轉(zhuǎn)運效率研究,中國生物醫(yī)學(xué)工程學(xué)報,2023,42(3):66-71
[5] Hongliang Wei*, Songmao Li, Zijun Liu,Hongli Chen*Yuhua Liu, Weikun Li, Gang Wang,Preparation and characterization of starch-cellulose interpenetrating network hydrogels based on sequential Diels-Alder click reaction and photopolymerization,International Journal of Biological Macromolecules,2022,194 (2022) 962–973
[6] Xuebin Song, Liqin Xie , Ming Zhang*, Wentao Wang , Lu Li , Xiaoyuan Lu , Peiyu Lei, Dan Liu , Yuming Chen ,Hongli Chen*, Changhong Zhao*,Cu-decorated graphene oxide coatings with enhanced antibacterial activity for surface modification of implant,Materials Research Bulletin, 2021, 141 : 111345
[7] HaiJiao Wang, WanYi Hou, YongWei Hao, WenShuai Jiang,HongLi Chen*, QiQing Zhang*,Novel yellow solid-state fluorescent-emitting carbon dots with high quantum yield for white light-emitting diodes, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 250:119340
[8] Guoyun Wan, Yuanyuan Cheng, JiaSong, Qian Chen, Bowei Chen, Yuanyuan Liua,Shenglu Ji,HongliChen*, YinsongWang*, Nucleus- targetingnear-infrared nanoparticlesbased on TAT peptide-conjugated IR780 forphoto- chemotherapy of breast cancer,Chemical Engineering Journal,2020, 380:122458
[9] Bowei Chen,Yajun Zhang, Ruixue Ran, Bin Wang, Furong Qin, Tao Zhang, Guoyun Wan,Hongli Chen*,Yinsong Wang*,Reactive oxygen species-responsive nanoparticles based on a thioketal-containing poly(β-amino ester) for combining photothermal/photodynamic therapy and chemotherapy, Polymer Chemistry, 2019,10:4746-4757
[10] Qin, Jingwen; Wei, Xiangjuan; Chen, Hongyang; Lv, Feng; Nan, Wenbin; Wang, Yongxue; Zhang, Qiqing*;Chen, Hongli*,mPEG-g-CS Modified PLGA Nanoparticle Carrier for the Co-delivery of Paclitaxel and Epirubicin for Breast Cancer Synergistic Therapy,ACS Biomaterials Science & Engineering,2018, 4 (5):1651–1660