王潔，1982.06-，中國科學院上海生命科學研究院生物化學與細胞生物學研究所細胞生物學博士學位。2013年入選新鄉(xiāng)醫(yī)學院首批“太行青年學者”。目前研究方向為分子免疫學，主要從事宿主抗病毒免疫機制研究。主持國家自然科學基金3項；以第一作者或通訊作者在Cellular & Molecular Immunology、J Immunol、FEBS Letter、Scientific Reports等雜志上發(fā)表論文8篇。 學術(shù)任職： 中國免疫學會會員 發(fā)表SCI論文一覽表（#為第一作者，*為通訊作者） Yang B, Song D, Liu Y, Cui Y, Lu G, Di W, Xing H, Ma L, Guo Z, Guan Y, Wang H, Wang J*. IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses. FEBS Lett. 2018 May; 592(10):1693-1704. doi: 10.1002/1873-3468.13077. IF=2.99 Wang J#, Song D, Liu Y, Lu G, Yang S, Liu L, Gao Z, Ma L, Guo Z, Zhang C,Wang H, Yang B. HLA-DMB restricts human T-cell leukemia virus type-1 (HTLV-1) protein expression via regulation of ATG7 acetylation. Sci Rep. 2017 Oct 31;7(1):14416. doi: 10.1038/s41598-017-14882-z. IF=4.8 Jie Wang#, Lixia Kang, Lu Liu, Shuai Yang, Di Song, Lingling Ma, Zhixiang Guo, Huaxia Ding, Hui Wang and Bo Yang. Ku70 senses the HTLV-1 DNA and modulates HTLV-1 replication. The Journal of immunology. 2017 Oct 1; 199(7):2475-2482. doi: 10.4049/jimmunol.1700111. IF=4.8 Jie Wang#, Shuai Yang, Lu Liu, Hui Wang and Bo Yang. HTLV-1 Tax impairs K63-linked ubiquitination of STING to evade host innate immunity. Virus research. 2017 Mar 15; 232:13-21. doi: 10.1016/j.virusres.2017.01.016. IF=2.7 Jie Wang#, Bo Yang, Yu Hu, Yuhan Zheng, Leilei Yang, Meilin Qin and Bing Sun. Negative regulation of Nmi on virus-triggered type I IFN production by targeting IRF7. The Journal of immunology. 2013 Sep 15; 191(6):3393-9. doi: 10.4049/jimmunol. IF=4.8 Bo Yang, Jie Wang#, Yanming Wang, Haiyan Zhou, Xiaodong Wu, Zhigang Tian, and Bing Sun. Novel function of Trim44 promotes an antiviral response by stabilizing VISA. The Journal of immunology. 2013 Apr 1; 190(7):3613-9. doi: 10.4049/jimmunol. IF=4.8 Yu Hu , Jie Wang#, Bo Yang, Meilin Qin, Yongyong Ji, Guomei Lin, Lin Tian, Xiaodong Wu and Bing Sun. Guanylate binding protein (GBP) 4 negatively regulates virus induced type I interferon and antiviral response by targeting interferon regulatory factor (IRF) 7.The Journal of immunology. 2011 Dec 15; 187(12):6456-62. doi: 10.4049/jimmunol.1003691. IF=4.8 Jie Wang#, Yu Hu , Wei Wen Deng, Bing Sun. Negative regulation of Toll-like receptor signaling pathway. Microbes and Infection. 2009 Mar; 11(3):321-7. doi: 10.1016/j.micinf.2008.12.011.IF=2.7
主持的重大科研項目： RNF144A調(diào)控MITA/STING介導的固有免疫應(yīng)答反應(yīng)的功能和機制研究，王潔，國家自然科學基金 2020.01-2023.12，No. 31970847，59萬元； RNF90調(diào)控MITA/STING介導的胞內(nèi)抗病毒應(yīng)答反應(yīng)的研究，王潔，國家自然科學基金 2017.01-2019.12，No. 31600697，20萬元； Ku70負性調(diào)控HTLV-1病毒感染的功能和機制研究，王潔，國家自然科學基金 2016.01-2018.12，No. U1504811，27萬元；
近五年來獲批專利： S100A10 mRNA在α-干擾素誘導抑郁癥中的作用(201510165415.9)，專利權(quán)人：王輝、郭繼強、張文、楊波、王潔、丁華夏、李桂芬
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