海南大學(xué)博士，新鄉(xiāng)醫(yī)學(xué)院精神神經(jīng)醫(yī)學(xué)研究院講師，碩士研究生導(dǎo)師，現(xiàn)從事蛋白質(zhì)棕櫚酰化修飾調(diào)控各類疾病發(fā)生發(fā)展的機制研究。主持國家自然科學(xué)基金青年科學(xué)基金項目：ZDHHC6介導(dǎo)的AEG-1棕櫚?；揎椪{(diào)控肝細胞癌發(fā)生發(fā)展的機制研究；河南省科學(xué)技術(shù)廳外國專家項目：zDHHC1調(diào)控泡沫細胞形成及動脈粥樣硬化進程的機制研究。近幾年以第一作者在國際期刊Cellular & Molecular Immunology、Theranostics、Frontiers in immunology、Molecular Oncology發(fā)表文章6篇，并參與發(fā)表Science China Life Sciences、PLoS Pathogens、Frontiers in Cell and Developmental Biology等多篇SCI論文。

研究方向:蛋白質(zhì)棕櫚?；揎椪{(diào)控各類疾病發(fā)生發(fā)展的機制研究

代表成果:

一、發(fā)表的論文

1.Zhou Binhui, Zhang Mengjie, Ma Haoyuan, et al. Distinct palmitoylation of Foxp3 regulates the function of regulatory T cells via palmitoyltransferases. Cell Mol Immunol. Published online May 8, 2024.

2. Binhui, Wang Ying, Zhang Lichen, et al. The palmitoylation of AEG-1 dynamically modulates the progression of hepatocellular carcinoma. Theranostics. 2022;12(16):6898-6914.

3.Zhou Binhui, Lawrence Toby, Liang Yinming. The Role of Plasmacytoid Dendritic Cells in Cancers. Front Immunol. 2021;12:749190.

4.Zhou Binhui, Yang Wenyi, Li Wushan, et al. Zdhhc2 Is Essential for Plasmacytoid Dendritic Cells Mediated Inflammatory Response in Psoriasis. Front Immunol. 2021;11:607442.

5.Zhou Binhui, Hao Qianyun, Liang Yinming, Kong Eryan. Protein palmitoylation in cancer: molecular functions and therapeutic potential. Mol Oncol. 2023;17(1):3-26.

6.Yang Wenyi, Zhou Binhui, Liu Qi, et al. A Murine Point Mutation of Sgpl1 Skin Is Enriched With Vγ6 IL17-Producing Cell and Revealed With Hyperpigmentation After Imiquimod Treatment. Front Immunol. 2022;13:728455.

二、主持的課題：

1. 國家自然科學(xué)基金青年基金項目，ZDHHC6介導(dǎo)的AEG-1棕櫚酰化修飾調(diào)控肝細胞癌發(fā)生發(fā)展的機制研究（32000491），2021.01-2023.12

2. 河南省科學(xué)技術(shù)廳外國專家項目，zDHHC1調(diào)控泡沫細胞形成及動脈粥樣硬化進程的機制研究（HNGD2023023），2023.01-2023.12

招生方向:細胞生物學(xué)

導(dǎo)師郵箱：zhoubinhui@126.com